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A Simcro solution is built on solid partnerships, genuine innovation and trusted ability to deliver. Our history in the pharmaceutical delivery industry goes back decades, but our focus is on the future. As the world grows, the pressure is on to develop more efficacious pharmaceutical treatments for production and companion animals. This can often mean creating compounds that are challenging or even dangerous to administer using traditional delivery system methodologies. Simcro has proven experience creating highly innovative solutions to administer these discoveries effectively, efficiently, and safely. Our most recent developments, such as the Optiline™ sheep drencher for Novartis Animal Health, the Sekurus™ safety injector family for Pfizer Animal Health, and the intramammary syringe for Merial, have all overcome significant challenges that previously had never been solved. These projects highlight Simcro's ability to deliver solutions that others can't imagine.We also know there's more to consider than simply delivering an unfailingly accurate dose. Our solutions are fully integrated and include primary and secondary packaging, protective shrouds and related accessories. A focus on animal welfare, operator safety, treatment efficacy, user experience and commercial viability are the hallmarks of our products. Simcro products enhance the value of our clients' brands.
Simcro Partners, Innovates and Delivers.
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With a significant and trusted record of partnerships with pharmaceutical companies, Simcro has demonstrated how it can cater to a wide variety of projects and individual client needs.
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Partner.
Innovate.
Deliver.
A Simcro solution is built on solid partnerships, genuine innovation and trusted ability to deliver. With a long history in pharmaceutical delivery our focus is on the future...
>> read more
World's First Self-tenting Injector
Pfizer issued Simcro with a demanding brief for a genuine two-stage safety injector that prevented self-injection without the risk of bruising the animal or causing it stress or discomfort...
>> read more
The Optiline Drencher
The Optiline drencher is the world's first in-line drencher and its unique design is no accident. The long list of features that have made it so popular stem from Simcro's ability to Partner, Innovate and Deliver...
>> read more
Simcro Packaging Solutions
Delivery systems are not simply an injector or an applicator. They are an integrated system from the product reservoir through to the point that the pharmaceutical product reaches the desired location...
>> read more
PARTNER. INNOVATE. DELIVER.
A Simcro solution is built on solid partnerships, genuine innovation and trusted ability to deliver. With a long history in pharmaceutical delivery our focus is on the future.
As the world grows, the pressure is on to develop more efficacious pharmaceutical treatments for production and companion animals. This can often mean creating compounds that are challenging or even dangerous to administer using traditional delivery system methodologies. Simcro has proven experience creating highly innovative solutions to administer these discoveries effectively, efficiently, and safely.
Our most recent developments, such as the Optiline™ sheep drencher for Novartis Animal Health, the Sekurus™ safety injector family for Pfizer Animal Health, and the intramammary syringe for Merial, have all overcome significant challenges that previously had never been solved. These projects highlight Simcro's ability to deliver solutions that others can't imagine.
We also know there's more to consider than simply delivering an unfailingly accurate dose. Our solutions are fully integrated and include primary and secondary packaging, protective shrouds and related accessories. A focus on animal welfare, operator safety, treatment efficacy, user experience and commercial viability are the hallmarks of our products. Simcro products enhance the value of our clients' brands.
Simcro Partners, Innovates and Delivers.
COLLABORATIVE, CONFIDENTIAL & PROFESSIONAL
Pharmaceutical development requires significant investment over long time frames under strict confidentiality. Pharmaceutical companies need partners who are innovative, professional and able to be trusted with confidential information.
Simcro has a significant record of partnering with the pharmaceutical industry globally, undertaking many highly confidential and market sensitive projects. We operate in a collaborative and professional manner with the complete confidence of our customers.
Our greatest breakthroughs are often the result of early project involvement. Many projects commence with a clean slate. The revolutionary in-line drench action of our Optiline™ sheep drencher is a prime example. A delivery method as innovative as the drench it administers. We're not afraid to challenge a brief if it improves the result.
These unique factors have been the difference for the world's largest pharmaceutical companies. Novartis, Pfizer, Merial and a number of other global pharmaceutical companies have partnered with Simcro to bring to market uniquely tailored, proprietary solutions.
CHALLENGING CURRENT THINKING
Simcro believes current thinking needs to be challenged. Many in-market products have not kept pace with the changes in materials technology or the expectations of today’s consumers, farmers and veterinary professionals. Our R&D team sees opportunities to converge a range of technologies into the pharmaceutical delivery industry.
The process of administering a pharmaceutical doesn’t end with the device in question. Simcro’s technology goes well beyond administering an accurate dose. Our solutions are measured against five primary criteria:
| > Animal Welfare |
| > Operator Safety |
| > Treatment Efficacy |
| > User Experience |
| > Commercial Viability |
 The Simcro innovation process will consider issues such as intended frequency of use, posture of the user, fluid viscosity at projected ambient temperatures as well as food chain integrity, user environment, and animal temperament.
Each development is viewed as a seamless part of an integrated delivery system focused on satisfying our five key criteria. Our primary packaging and bottle protection innovations are often important and sometimes overlooked components of a successful pharmaceutical delivery solution.
A REPUTATION FOR ACCURACY AND USER EXPERIENCE
The Simcro R&D team manages the product development process through to the production ready stage, at which point the quality assurance, production and marketing teams manage the products transition through to commercialisation. Our reputation for delivering is exemplified by the long-standing relationships we have with our customers.
We understand that even the most innovative solutions still have to be commercially feasible in the real world. Our projects consider the commercial realities from the outset, with special attention given to ease of manufacture, quality assurance and shelf presentation.
As a result of our stringent quality expectations and innovative development approach, Simcro products enhance the brand value of the pharmaceutical that they deliver. Our reputation for accuracy and user experience spans nearly two decades and we see ourselves as a companion to global pharmaceutical brands.
We can also tailor our proprietary range of products to suit our clients’ brands or designs, adding the value of the Simcro reputation for accuracy and delivery.
SEKURUS™ WORLD'S FIRST
SELF-TENTING INJECTOR
In 2004 Pfizer Animal Health issued Simcro with a demanding brief, to create a genuine two-stage safety injector that minimised the risk of self-injection by the user, administered the product at a precise depth to ensure efficacy, and satisfied animal welfare criteria.
Several concepts were trialled, but none that our development engineers were happy to present to Pfizer until 2007 when the patented double over-centre hinge concept was developed which is the genius within Sekurus™. This concept gave birth to the safety injector that Pfizer had been looking for and allowed the further development of the patented self-tenting needle guard. Together these innovations have created the ability to perform one-handed subcutaneous injections, completely satisfying the original challenge presented by Pfizer.
The design of the Sekurus™ has several additional benefits:
| > The protective needle guard ensures the risk of self-injection is minimised, even when Sekurus™ is not in use. |
| > The two-stage action specific to Sekurus™ ensures that administration of the pharmaceutical will not occur until the needle reaches maximum penetration depth. |
| > The potential for needle breakage during operation is significantly reduced maintaining a high level of food chain integrity. |
| > Administering a one-handed subcutaneous injection is far easier and less hazardous for the operator than two-handed techniques, particularly in confined spaces such as cattle crush. |
| > One-handed injection techniques are much less invasive of an animal's space, particularly in the head region, reducing stress and animal discomfort. |
| > The needle guard makes needle changeover a much safer and faster task, reducing the risk of needle-stick injuries. |
| > Increased administration speed by proficient users of Sekurus™. |
The Sekurus™ has won numerous design awards for its innovative design and proven accuracy. It reflects Simcro's commitment to the principles of animal welfare, operator safety, treatment efficacy, user experience and commercial viability.
THE OPTILINE™ DRENCHER
The Optiline™ sheep drencher is the world's first in-line drencher and its unique design is no accident. The long list of features that have made it so popular stem from Simcro's ability to Partner, Innovate and Deliver.
Novartis were looking for a delivery solution for ZOLVIX® the ground breaking sheep drench and first new class of anthelmintic in over 25 years. Novartis was clear in their requirements; they wanted a drenching system that would be as revolutionary as the product it delivered. In typical Simcro fashion, the technical team conceptualised delivery systems that were a radical departure from the traditional delivery systems that would raise the bar significantly for what farmers would expect in drenching equipment. Novartis selected Simcro as the development partner because they had complete confidence in our innovation, our technical abilities and proven track record of maintaining strict confidentiality.
The core of the Optiline™ solution came from Simcro’s unique approach to innovation. We avoid getting stuck in any one method of application, considering all possibilities before deciding on a final concept. The in-line drench method at the heart of the Optiline™ may seem familiar to those with hands-on experience in the farming
industry. It uses the same hand and arm positioning as drenching with a bottle, although the similarities stop there. With an ergonomic mode of action, patented dose lock, internal valving technology, and a unique nozzle design, the Optiline™ sheep drencher has transformed the way sheep will be drenched in the future.
The commercialized Optiline™ sheep drencher is completely tailored to Novartis requirements with Simcro exceeding expectations throughout the project. While the brief may have been for a drencher, the Optiline's success has come through Simcro’s collaboration with Novartis in all aspects of the delivery system, from backpacks and harness through to the drencher itself. The true mark of Simcro’s success has been the very successful commercial launch of ZOLVIX®, in part attributable to the innovative method of application.
DECEPTIVELY SIMPLE PROTECTION
Delivery systems are not simply an injector or an applicator. They are an integrated system from the product reservoir through to the point that the pharmaceutical product reaches the desired location.
Our design capability and experience enables Simcro to consider all aspects of the delivery system from primary and secondary packaging, to bottle protectors, fluid transfer components and the delivery device itself, ensuring the entire system will successfully deliver the pharmaceutical product to the customers expectations.
Take our bottle protector for Draxxin® as an example. The Simcro bottle protector looks deceptively simple. In fact, a bottle within this sleeve can survive a 1.2m fall onto a concrete surface at -20°C without risk of breakage.
Within this innovative design, Simcro have allowed for the two Draxxin® bottles of the same volumetric size, yet quite different shapes, to be fully protected when fitted into the sleeve. This is achieved by securing the bottle with two sets of snap tabs, ensuring that the product, in either bottle, is held secure while allowing easy loading and reloading as the job demands. Like many Simcro solutions, the Draxxin® bottle sleeve is well-engineered simplicity.
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